Explore: The Journal of Science and Healing
Volume 2, Issue 6 , Pages 488-494 , November 2006

Glyconutrients: The State of the Science and the Impact of Glycomics

  • Victor S. Sierpina, MD

      Affiliations

    • Department of Family Medicine, University of Texas Medical Branch, Galveston, TX
    • Corresponding Author InformationCorresponding author. Address: 301 University, Galveston, TX 77555-1123.
    • ,
  • Robert K. Murray, MD, PhD

      Affiliations

    • Professor (Emeritus), Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

References 

  1. In:  Varki A,  Cummings R,  Esko J,  Freeze H,  Hart G,  Marth J, et al. editor. Essentials of Glycobiology. Cold Spring Harbor, MA: Cold Spring Harbor Laboratory Press; 1999;
  2. Taylor ME, Drickamer K. Introduction to Glycobiology. Oxford, UK: Oxford University Press; 2003;
  3. Murray RK, Mayes P, Rodwell V, Granner D. Harper’s Illustrated Biochemistry. 27th ed. St. Louis, MO: McGraw-Hill; 2006;
  4. Sharon N, Ofek I. Safe as mother’s milk: carbohydrates as future anti-adhesion drugs for bacterial diseases. Glycoconj J. 2000;17:659–664
  5. Carbohydrates and glycobiology. Science. 2001;291:2337–2378
  6. Sasisekharan R, Myett JR. The Sweet Science of Glycobiology. American Scientist Online. 2003;91:432;Available at: http://www.americanscientist.org/template/IssueTOC/issue/400. Accessed October 11, 2006.
  7. Axford J. 7th Jenner Glycobiology and Medicine Symposium. Sept 5- 8, 2004 Adv Ex Med Biol. 2005;564:v–viii
  8. McAlindon TE, LaValley MP, Gulin JP, Felson DT. Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta-analysis. JAMA. 2000;283:1469–1475
  9. Richy F, Bruyere O, Ethgen O, et al. Structural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysis. Arch Int Med. 2003;163:1514–1522
  10. Clegg DO, Reda DJ, Harris CL, et al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Eng J Med. 2006;354:795–808
  11. Mondoa E, Kitei M. Sugars that Heal: The New Healing Science of Glyconutrients. New York, NY: Ballantine; 2001;
  12. Elkins R. Miracle Sugars. Pleasant Grove, Utah: Woodland Publishing; 2002;
  13. Pippenger CE, VanderWal MC, Kurlandsky LE, et al. Evaluation of the Potential Efficacy of Glyconutrient and Phytonutrient Supplementation in the Clinical Management of Asthma. 2006;Presented at the 7th Jenner Glycobiology & Medicine Symposium, Sept 5-8, 2004, Exeter College, Oxford, UK. Published in Proceedings of the Fisher Institute for Medical Research. Available at http://www.FisherInstitute.org. Accessed October 11
  14. VanderWal MC, Pippenger CE. A Retrospective Post-Marketing Survey of Clinical Symptom Changes in a Cystic Fibrosis Population Voluntarily Supplementing Their Diets with Glyconutrition: Clinical Symptom Changes. 2006;Presented at the 7th Jenner Glycobiology & Medicine Symposium, Sept 5-8, 2004, Exeter College, Oxford, UK Published in Proceedings of the Fisher Institute for Medical Research. Available at http://www.FisherInstitute.org. Accessed October 11
  15. Randell DJ, Byars A, Williams F, Miller L. The Effects of Nutraceutical Dietary Intervention in Myasthenia Gravis. 2006;Presented at Annual Meeting of Myasthenia Gravis Foundation, Sept 24, 2005, San Diego, CA. Published in Proceedings of the Fisher Institute for Medical Research. Available at http://www.FisherInstitute.org. Accessed October 11
  16. Arcadi VC, Dykman K. Case study: Tay-Sachs disease improvement during nutritional supplementation. JANA. 1997;1(S):26–27
  17. Dykman K, Gardiner T, Ford CR, Horn E. The effects of long-term supplementation on the functionality and use of non-drug therapies in patients diagnosed with fibromyalgia and chronic fatigue syndrome. 2001;Presented at: Experimental Biology 2001; March 31-April 4; Orlando, Fla.
  18. Dykman KD, Dykman RA. Effect of nutritional supplements on attention-deficit hyperactivity disorder. Integr Physiol Behav Sci. 1998;3:49–60
  19. McDaniel CF, Dykman K, McDaniel HR, Ford CR, Tone CM. Effects of nutraceutical dietary intervention in diabetes mellitus: a retrospective survey. 2006;Proceedings of the Fisher Institute for Medical Research. Available at http://www.FisherInstitute.org. Accessed October 11
  20. Axford JS. Review of glycosylation and rheumatic disease. Biochim Biophys Acta. 1999;1445:219–229
  21. Russell AL. Glycosaminoglycan (GAG) deficiency in protective barrier as an underlying primary cause of ulcerative colitis, Crohn’s disease, interstitial cystitis and possibly Reiter’s syndrome. Med Hypoth. 1999;52:297–301
  22. GlycoScience. Available at: http://www.glycoScience.org. Accessed October 11, 2006.
  23. The Proceedings of the Fisher Institute for Medical Research. Available at http://www.FisherInstitute.org. Accessed October 11, 2006.
  24. Axford J. Glycobiology and medicine: an introduction. J R Soc Med. 1997;90:260–264
  25. Maeder T. Sweet medicines. Scientific American. 2002;41–47July

PII: S1550-8307(06)00416-2

doi: 10.1016/j.explore.2006.08.016

Explore: The Journal of Science and Healing
Volume 2, Issue 6 , Pages 488-494 , November 2006

Article Tools

* Image Usage & Resolution